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Coregulation and modulation of NF B-related genes in celiac disease: uncovered aspects of gut mucosal inflammation

24 Oct 2013

Abstract excerpt

It is known that the NFκB route is constitutively upregulated in celiac disease (CD), an immune-mediated disorder of the gut caused by intolerance to ingested gluten. Our aim was to scrutinize the expression patterns of several of the most biologically relevant components of the NFκB route in intestinal biopsies from active and treated patients and after in vitro gliadin challenge, and to assess normalization of...

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PMID: 24163129
DOI: 10.1093/hmg/ddt520

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