Article
Molecular modeling of the von Willebrand factor A2 Domain and the effects of associated type 2A von Willebrand disease mutations.
Journal of molecular modeling - 1 Aug 2004
Sutherland Jeffrey J, O'Brien Lee A, Lillicrap David, Weaver Donald F
Abstract excerpt
A homology model for the A2 domain of von Willebrand factor (VWF) is presented. A large number of target-template alignments were combined into a consensus alignment and used for constructing the model from the structures of six template proteins. Molecular dynamics simulation was used to study t...
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