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Article

Lessons from molecular modeling human α-L-iduronidase.

Journal of molecular graphics & modelling - 1 Nov 2014

Figueiredo Danieli Forgiarini, Antunes Dinler A, Rigo Maurício M, Mendes Marcus F A, Silva Jader P, Mayer Fabiana Q, Matte Ursula, Giugliani Roberto, Vieira Gustavo F, Sinigaglia Marialva

Abstract excerpt

Human α-L-iduronidase (IDUA) is a member of glycoside hydrolase family and is involved in the catabolism of glycosaminoglycans (GAGs), heparan sulfate (HS) and dermatan sulfate (DS). Mutations in this enzyme are responsible for mucopolysaccharidosis I (MPS I), an inherited lysosomal storage disor...

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Source

Identifiers

PMID: 25459762
DOI: 10.1016/j.jmgm.2014.10.004

Genes

IDUA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25459762-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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