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Article

The cyclic AMP-dependent protein kinase a network regulates development and virulence in Aspergillus fumigatus.

Infection and immunity - 1 Sept 2004

Liebmann Burghard, Müller Meike, Braun Armin, Brakhage Axel A

Abstract excerpt

Aspergillus fumigatus is an important pathogen of immunocompromised hosts, causing pneumonia and invasive disseminated disease with high mortality. To determine the importance of the cyclic AMP (cAMP) signaling pathway for virulence, the pkaC1 gene encoding a protein kinase A (PKA) catalytic subunit was cloned and characterized. Deletion of pkaC1 led to reduced conidiation and growth. PKA activity was not...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15322014
DOI: 10.1128/IAI.72.9.5193-5203.2004
PMCID: PMC517480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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