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Article

Effects of sarA inactivation on the intrinsic multidrug resistance mechanism of Staphylococcus aureus.

FEMS microbiology letters - 15 Aug 2004

O'Leary Jessica O, Langevin Mark J, Price Christopher T D, Blevins Jon S, Smeltzer Mark S, Gustafson John E

Abstract excerpt

The sarA locus of Staphylococccus aureus regulates the synthesis of over 100 genes on the S. aureus chromosome. We now report the effects of sarA inactivation on intrinsic multidrug resistance expression by S. aureus. In a strain-dependent fashion, sarA::kan mutants of three unrelated strains of S. aureus demonstrated significantly increased susceptibility to five or more of the following substances: the...

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Identifiers

PMID: 15321676
DOI: 10.1016/j.femsle.2004.06.047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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