Article
Inheritance of urinary calculi in the Dalmatian.
Journal of veterinary internal medicine - 1 Jan 2000
Bannasch D L, Ling G V, Bea J, Famula T R
Abstract excerpt
Dalmatians are unique among dogs in that they excrete uric acid in their urine as the end product of purine metabolism rather than allantoin as do other breeds of dogs. Urinary calculi form from urate (salts of uric acid) and can cause urethral obstruction in male Dalmatians. Although all Dalmatians have the primary defect, only a subset develops clinical disease. We postulated that calculi formation might have a...
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