Article
Validation of a urine test and characterization of the putative genetic mutation for hyperuricosuria in Bulldogs and Black Russian Terriers.
American journal of veterinary research - 1 Aug 2010
Karmi Nili, Safra Noa, Young Amy, Bannasch Danika L
Abstract excerpt
OBJECTIVE: To determine whether hyperuricosuria was a predisposing factor for urate urolithiasis in Bulldogs and Black Russian Terriers (BRTs) and to estimate the allele frequency of the Cys181Phe genetic mutation in urate transporter SLC2A9 in these breeds. ANIMALS: 192 Bulldogs, 101 BRTs, 10 Dalmatians, and 9 dogs of other breeds. PROCEDURES: Uric acid (UA) and creatinine (Cr) concentrations were quantified in...
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