Article
Identification of a soluble GM-CSF binding protein in the supernatant of a human choriocarcinoma cell line.
Biochemical and biophysical research communications - 28 Feb 1992
Sasaki K, Chiba S, Mano H, Yazaki Y, Hirai H
Abstract excerpt
We identified two forms of the receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF) made by the human choriocarcinoma cell line JEG-3 using an affinity-labeling technique. The protein was identified in the detergent-extract was 78 kDa, very similar to that of the membrane-bound GM-CSF receptor alpha chain expressed in a wide variety of hematopoietic and nonhematopoietic cells, including JEG-3....
Topics
- Choriocarcinoma
- Female
- Genetic Variation
- Humans
- Membranes
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
- Solubility
- Tumor Cells, Cultured
- Uterine Neoplasms