Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of C/EBP -LIP, a Naturally Occurring, Dominant-Negative Transcription Factor, in Human Breast Cancer

17 Dec 1997

Abstract excerpt

BACKGROUND: When cells fail to maintain a balance between proliferation, terminal differentiation, and programmed cell death, cancer often results. The CCAAT/enhancer-binding protein (C/EBP) family of transcription factors regulates many genes involved in the processes of proliferation and terminal differentiation. The messenger RNA for C/EBPbeta is translated into two major isoforms, LAP (liver-enriched...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9414177
DOI: 10.1093/jnci/89.24.1887

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of C/EBP -LIP, a Naturally Occurring, Dominant-Negative Transcription Factor, in Human Breast CancerPMID 9414177Read ↗

C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cellsSemantic proximity Read ↗

The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.Semantic proximity Read ↗

Identification of Cyclin D1– and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and ProgressionSemantic proximity Read ↗

Transcription Factor EB Expression in Early Breast Cancer Relates to Lysosomal/Autophagosomal Markers and PrognosisSemantic proximity Read ↗

Liver-enriched inhibitory protein (LIP) actively inhibits preadipocyte differentiation through histone deacetylase 1 (HDAC1).Semantic proximity Read ↗

Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling CascadeSemantic proximity Read ↗

Orthogonal analysis of C/EBPbeta targets in vivo during liver proliferation.Semantic proximity Read ↗

The Many Faces of C/EBPδ and their Relevance for Inflammation and CancerSemantic proximity Read ↗

Differential Control of the CCAAT/Enhancer-binding Protein β (C/EBPβ) Products Liver-enriched Transcriptional Activating Protein (LAP) and Liver-enriched Transcriptional Inhibitory Protein (LIP) and the Regulation of Gene Expression during the Response to Endoplasmic Reticulum StressSemantic proximity Read ↗

A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype.Semantic proximity Read ↗

Ectopic expression of the ErbB-3 binding protein Ebp1 inhibits growth and induces differentiation of human breast cancer cell linesSemantic proximity Read ↗

Functional association of PR and CCAAT/enhancer-binding protein beta isoforms: promoter-dependent cooperation between PR-B and liver-enriched inhibitory protein, or liver-enriched activatory protein and PR-A in human endometrial stromal cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.