Article
Protection against Japanese encephalitis virus strains representing four genotypes by passive transfer of sera raised against ChimeriVax-JE experimental vaccine.
Vaccine - 9 Sept 2004
Beasley David W C, Li Li, Suderman Miguel T, Guirakhoo Farshad, Trent Dennis W, Monath Thomas P, Shope Robert E, Barrett Alan D T
Abstract excerpt
The ability of antisera raised against a candidate Japanese encephalitis virus (JEV) vaccine, ChimeriVax-JE, and the currently licensed vaccine, JE-VAX, to protect against strains of JEV representing the four major genotypes was assessed. Neutralization assays and passive protection studies in mice showed that greatest protection was provided against strains of genotypes II and III, although some protection was...
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