Article
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.
The Journal of cell biology - 16 Aug 2004
Kitajiri Shin-ichiro, Fukumoto Kanehisa, Hata Masaki, Sasaki Hiroyuki, Katsuno Tatsuya, Nakagawa Takayuki, Ito Juichi, Tsukita Shoichiro, Tsukita Sachiko
Abstract excerpt
Ezrin/radixin/moesin (ERM) proteins cross-link actin filaments to plasma membranes to integrate the function of cortical layers, especially microvilli. We found that in cochlear and vestibular sensory hair cells of adult wild-type mice, radixin was specifically enriched in stereocilia, specially...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.