Article
Mutations and variants of apolipoprotein B that affect plasma cholesterol levels.
Advances in experimental medicine and biology - 1 Jan 1991
Innerarity T L, Boström K
Abstract excerpt
Apolipoprotein (apo-) B100 is the exclusive apolipoprotein of low density lipoproteins (LDL0, which transport most of the plasma cholesterol in humans. Mutations in apo-B100 can cause either hypocholesterolemia or hypercholesterolemia. Familial hypobetalipoproteinemia, which leads to hypocholesterolemia, has been shown to be caused by defects in the apo-B gene that terminate translation prematurely and result in...
Topics
- Apolipoprotein B-48
- Apolipoproteins B
- Cholesterol
- Humans
- Mutation