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Bacterial DNA within Granulomas of Patients with Crohn's Disease-Detection by Laser Capture Microdissection and PCR

1 Aug 2004

Abstract excerpt

OBJECTIVES: We previously reported the use of laser capture microdissection (LCM) and PCR to detect the presence of Mycobacterium paratuberculosis DNA in granulomas of patients with Crohn's disease. While this does not imply a cause-effect relationship, it may influence the disease process because bacterial DNA has immunomodulatory effects. The aim of this study was to determine whether DNA from nonmycobacterial...

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PMID: 15307874
DOI: 10.1111/j.1572-0241.2004.40103.x

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