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Detection of bacterial DNA in lymph nodes of Crohn's disease patients using high throughput sequencing

15 Jan 2014

Abstract excerpt

OBJECTIVE: Our aim was to determine whether or not specific microorganisms were transported selectively to lymph nodes in Crohn's disease (CD) by comparing node and mucosal microbial communities in patients and controls. We also sought evidence of dysbiosis and bacterial translocation. DESIGN: Lymph nodes, and involved and uninvolved mucosal samples were obtained from resections of 58 patients (29 CD, eight...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24429583
DOI: 10.1136/gutjnl-2013-305320

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