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Specific detection of Mycobacterium paratuberculosis DNA associated with granulomatous tissue in Crohn's disease.

1 Apr 1994

Abstract excerpt

The role of mycobacteria, specifically Mycobacterium paratuberculosis, in Crohn's disease has aroused considerable controversy for many years. Using the ultra sensitive polymerase chain reaction some studies have reported detection of M paratuberculosis DNA in as many as 65% of Crohn's disease patients but also in patients without disease. Other studies have been negative for both groups. We therefore designed a...

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Identifiers

PMID: 8174989
DOI: 10.1136/gut.35.4.506

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