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Article

MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision.

Proceedings of the National Academy of Sciences of the United States of America - 30 Aug 2005

Johnston Robert J, Chang Sarah, Etchberger John F, Ortiz Christopher O, Hobert Oliver

Abstract excerpt

The elucidation of the architecture of gene regulatory networks that control cell-type specific gene expression programs represents a major challenge in developmental biology. We describe here a cell fate decision between two alternative neuronal fates and the architecture of a gene regulatory network that controls this cell fate decision. The two Caenorhabditis elegans taste receptor neurons "ASE left" (ASEL)...

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Identifiers

PMID: 16099833
DOI: 10.1073/pnas.0505530102
PMCID: PMC1194938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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