Article
Viral evolution and the emergence of SARS coronavirus.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Jul 2004
Holmes Edward C, Rambaut Andrew
Abstract excerpt
The recent appearance of severe acute respiratory syndrome coronavirus (SARS-CoV) highlights the continual threat to human health posed by emerging viruses. However, the central processes in the evolution of emerging viruses are unclear, particularly the selection pressures faced by viruses in new host species. We outline some of the key evolutionary genetic aspects of viral emergence. We emphasize that, although...
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