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Article

[Prediction of insulin-dependent diabetes mellitus in children of first-degree relatives of diabetic patients].

Casopis lekaru ceskych - 1 Aug 2001

Cinek O, Kolousková S, Pechová M, Sumník Z, Sedláková P, Bendukidze N, Ivasková E, Snajderová M, Vavrinec J

Abstract excerpt

BACKGROUND: Individuals at risk for insulin dependent diabetes mellitus (IDDM) can be identified using a combination of genetic, immunological and metabolic markers. Our study was aimed at prediction of IDDM in a cohort of children having a first-degree relative with IDDM. METHODS AND RESULTS: In the period of three years, we investigated 208 non-diabetic children and adolescents, aged 10.0 +/- 5.3 (mean +/- SD),...

Topics

Adolescent
Autoantibodies
Child
Diabetes Mellitus, Type 1
Female
Genetic Predisposition to Disease
Genotype
Glucose Tolerance Test
Glutamate Decarboxylase
HLA-DQ Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Isoenzymes

Male

Risk Factors

Source

Identifiers

PMID: 11678027

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