Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gpr1, a Putative G-Protein-Coupled Receptor, Regulates Morphogenesis and Hypha Formation in the Pathogenic Fungus <i>Candida albicans</i>

1 Aug 2004

Abstract excerpt

In response to various extracellular signals, the morphology of the human fungal pathogen Candida albicans switches from yeast to hypha form. Here, we report that GPR1 encoding a putative G-protein-coupled receptor and GPA2 encoding a Galpha subunit are required for hypha formation and morphogenesis in C. albicans. Mutants lacking Gpr1 (gpr1/gpr1) or Gpa2 (gpa2/gpa2) are defective in hypha formation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15302825
DOI: 10.1128/ec.3.4.919-931.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gpr1, a Putative G-Protein-Coupled Receptor, Regulates Morphogenesis and Hypha Formation in the Pathogenic Fungus <i>Candida albicans</i>PMID 15302825Read ↗

The G Protein-coupled Receptor Gpr1 and the Gα Protein Gpa2 Act through the cAMP-Protein Kinase A Pathway to Induce Morphogenesis in <i>Candida albicans</i>Semantic proximity Read ↗

<i>Aspergillus fumigatus</i> G-protein coupled receptors GprM and GprJ are important for the regulation of the cell wall integrity pathway, secondary metabolite production, and virulenceSemantic proximity Read ↗

PHR1, a pH-regulated gene of Candida albicans encoding a glucan-remodelling enzyme, is required for adhesion and invasion.Semantic proximity Read ↗

Combined inactivation of the Candida albicans GPR1 and TPS2 genes results in avirulence in a mouse model for systemic infection.Semantic proximity Read ↗

Gpa2, a G-protein alpha subunit required for hyphal development in Candida albicans.Semantic proximity Read ↗

The Ras/cAMP/PKA signaling pathway and virulence in <i>Candida albicans</i>Semantic proximity Read ↗

Co-regulation of pathogenesis with dimorphism and phenotypic switching in Candida albicans, a commensal and a pathogen.Semantic proximity Read ↗

Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in <i>Candida albicans</i>Semantic proximity Read ↗

Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of <i>Candida albicans</i>Semantic proximity Read ↗

PHR1, a pH-regulated gene of Candida albicans, is required for morphogenesis.Semantic proximity Read ↗

<i>Candida albicans</i> filamentation does not require the cAMP-PKA pathway in vivoSemantic proximity Read ↗

A putative G protein-coupled receptor negatively controls sexual development in Aspergillus nidulans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.