Article
The DNA double-stranded break repair protein endo-exonuclease as a therapeutic target for cancer
1 Aug 2004
Abstract excerpt
DNA repair mechanisms are crucial for the maintenance of genomic stability and are emerging as potential therapeutic targets for cancer. In this study, we report that the endo-exonuclease, a protein involved in the recombination repair process of the DNA double-stranded break pathway, is overexpressed in a variety of cancer cells and could represent an effective target for developing anticancer drugs. We identify...
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