Article
Fine localization of Nefl and Nef3 and its exclusion as candidate gene for lens rupture 2(lr2).
Experimental animals - 1 Jul 2004
Rhee Sang Dal, Kim Eunmin, Yoon Sungjoo Kim, Yang Sung-Don, Okumoto Masaaki, Han Sang-Seop, Song Chang-Woo
Abstract excerpt
Cataract causing lr2 gene is found in the CXSD mouse, which is a recombinant inbred strain of BALB/c and STS mice. For the process of positional cloning of lr2, several candidate genes were selected in the middle region of chromosome 14, but most of them were excluded by combination of recombination and homozygosity mapping. Components of neurofilament proteins, neurofilament light polypeptide (Nefl) and...
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