Article
The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.
Development (Cambridge, England) - 1 Mar 2007
Uhrig Joachim F, Mutondo Moola, Zimmermann Ilona, Deeks Michael J, Machesky Laura M, Thomas Philipp, Uhrig Silke, Rambke Claudia, Hussey Patrick J, Hülskamp Martin
Abstract excerpt
The actin-nucleating ARP2-ARP3 complex controls cell shape in plants in many different cell types. Its activity is controlled by a multimeric complex containing BRK1 (also known as HSPC300), NAP1, SRA1, ABI and SCAR/WAVE. In this study, we focus on the function of the five putative SCAR homologues in Arabidopsis and we provide biochemical evidence that AtSCAR2 can activate the ARP2-ARP3 complex in vitro. Among...
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