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Article

Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.

Development (Cambridge, England) - 1 Sept 2004

Basu Dipanwita, El-Assal Salah El-Din, Le Jie, Mallery Eileen L, Szymanski Daniel B

Abstract excerpt

The WAVE complex is an essential regulator of actin-related protein (ARP) 2/3-dependent actin filament nucleation and cell shape change in migrating cells. Although the composition of the WAVE complex is well characterized, the cellular mechanisms that control its activity and localization are not well known. The 'distorted group' defines a set of Arabidopsis genes that are required to remodel the actin...

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Source

Identifiers

PMID: 15294869
DOI: 10.1242/dev.01307

Genes

SRA1
RHO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.PMID 15294869Read ↗

Arabidopsis GNARLED encodes a NAP125 homolog that positively regulates ARP2/3.Semantic proximity Read ↗

NAPP and PIRP encode subunits of a putative wave regulatory protein complex involved in plant cell morphogenesis.Semantic proximity Read ↗

DISTORTED3/SCAR2 is a putative arabidopsis WAVE complex subunit that activates the Arp2/3 complex and is required for epidermal morphogenesis.Semantic proximity Read ↗

Requirements for Arabidopsis ATARP2 and ATARP3 during epidermal development.Semantic proximity Read ↗

The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.Semantic proximity Read ↗

Arabidopsis BRICK1/HSPC300 is an essential WAVE-complex subunit that selectively stabilizes the Arp2/3 activator SCAR2.Semantic proximity Read ↗

A role for ABIL3 in plant cell morphogenesis.Semantic proximity Read ↗

BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis.Semantic proximity Read ↗

Mutations in actin-related proteins 2 and 3 affect cell shape development in Arabidopsis.Semantic proximity Read ↗

Breaking the WAVE complex: the point of Arabidopsis trichomes.Semantic proximity Read ↗

The Arabidopsis KLUNKER gene controls cell shape changes and encodes the AtSRA1 homolog.Semantic proximity Read ↗

Activation of Arp2/3 complex-dependent actin polymerization by plant proteins distantly related to Scar/WAVESemantic proximity Read ↗

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