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Article

Genetic instability of heterozygous, hybrid, natural wine yeasts.

Applied and environmental microbiology - 1 Aug 2004

Ramírez Manuel, Vinagre Antonia, Ambrona Jesús, Molina Felipe, Maqueda Matilde, Rebollo José E

Abstract excerpt

We describe a genetic instability found in natural wine yeasts but not in the common laboratory strains of Saccharomyces cerevisiae. Spontaneous cyh2(R)/cyh2(R) mutants resistant to high levels of cycloheximide can be directly isolated from cyh2(S)/cyh2(S) wine yeasts. Heterozygous cyh2(R)/cyh2(S) hybrid clones vary in genetic instability as measured by loss of heterozygosity at cyh2. There were two main classes...

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Identifiers

PMID: 15294803
DOI: 10.1128/AEM.70.8.4686-4691.2004
PMCID: PMC492439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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