Article
Islet-derived multipotential cells/progenitor cells.
Cell biochemistry and biophysics - 1 Jan 2004
Teitelman Gladys
Abstract excerpt
The pancreatic beta-cell has a pivotal role in the regulation of glucose homeostasis; its death leads to type I diabetes. Neogenesis of beta-cells, the differentiation of beta-cells from non-beta-cells, could be an important mechanism of islet cell repopulation. To examine the ability of the adult pancreas to generate new beta-cells, we characterized the phenotype of beta precursor cells in embryos and then...
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