Article
Ameloblastin gene (AMBN) mutations associated with epithelial odontogenic tumors.
Oral oncology - 1 Sept 2004
Perdigão P F, Gomez R S, Pimenta F J G S, De Marco L
Abstract excerpt
Ameloblastin (AMBN, MIM *601259) gene expresses an important protein (AMBN), present in the organic matrix of enamel. The AMBN protein has an important role in the differentiation of ameloblast cells and epithelium-mesenchyme signaling during odontogenesis which prompted us to investigate this gene in aggressive epithelial odontogenic tumors, such as ameloblastomas, and in some non-aggressive ones, such as the...
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