Article
[Mutation and polymorphism of the ameloblastin gene in ameloblastomas].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology - 1 Nov 2006
Niu Chun-hua, Li Tie-jun
Abstract excerpt
OBJECTIVE: To investigate the presence of mutation or polymorphism of ameloblastin (AMBN) gene in ameloblastomas. METHODS: Genomic DNA was extracted from frozen tissues of 10 ameloblastomas and one malignant ameloblastoma. AMBN gene alterations were detected by PCR-direct sequencing. Restriction fragment length polymorphism (RFLP) analysis was used to further determine the nature of the changes in AMBN detected...
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