Article
A study of some hepatic immunological markers, iron load and virus genotype in chronic hepatitis C.
Journal of hepatology - 1 Aug 2004
Cardoso Elsa Maria, Duarte Miguel Angelo, Ribeiro Eduarda, Rodrigues Pedro, Hultcrantz Rolf, Sampaio Paula, Ehrlich Rachel, Carvalho João, Fraga José, de Sousa Maria
Abstract excerpt
BACKGROUND/AIMS: Host factors that may influence progression of hepatitis C infection to chronic hepatitis include T-cell responses and iron accumulation. We evaluated the hepatic expression of immunological markers relevant for a cytotoxic response in relation to viral and HFE genotype. METHODS: Frozen liver biopsies were obtained at diagnosis from 28 HFE genotyped patients. Sections stained for CD8, MHC-I,...
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