Article
Inflamm-aging: autoimmunity, and the immune-risk phenotype.
Autoimmunity reviews - 1 Jul 2004
Boren Eric, Gershwin M Eric
Abstract excerpt
Aging of the immune system, or immunosenescence, is a complex subject best defined as a decline in cell-mediated immunity, particularly with respect to T cell function. Paradoxically with the decline in immune function is an increase in autoantibody frequency. It has been postulated that the accumulation of anamnestic cells over time and/or environmental/infectious mimics leads to the production of...
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