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Immunosenescence, inflammation and Alzheimer’s disease

1 Nov 2012

Abstract excerpt

Ageing impacts negatively on the development of the immune system and its ability to fight pathogens. Progressive changes in the T-cell and B-cell systems over the lifespan of individuals have a major impact on the capacity to respond to immune challenges. The cumulative age-associated changes in immune competence are termed immunosenescence that is characterized by changes where adaptive immunity deteriorates,...

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PMID: 24764513
DOI: 10.1186/2046-2395-1-8

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