Article
C4BQ0: a genetic marker of familial HCV-related liver cirrhosis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jul 2004
Pasta L, Pietrosi G, Marrone C, D'Amico G, D'Amico M, Licata A, Misiano G, Madonia S, Mercadante F, Pagliaro L
Abstract excerpt
BACKGROUND AND METHODS: Host may have a role in the evolution of chronic HCV liver disease. We performed two cross-sectional prospective studies to evaluate the prevalence of cirrhosis in first degree relatives of patients with cirrhosis and the role of two major histocompatibility complex class III alleles BF and C4 versus HCV as risk factors for familial clustering. FINDINGS: Ninety-three (18.6%) of 500...
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