Article
Evidence for a dominant major gene conferring predisposition to hepatitis C virus infection in endemic conditions.
Human genetics - 1 Nov 2009
Laouénan Cédric, Plancoulaine Sabine, Mohamed Mostafa Kamal, Arafa Naglaa, Bakr Iman, Abdel-Hamid Mohamed, Rekacewicz Claire, Obach Dorothée, Fontanet Arnaud, Abel Laurent
Abstract excerpt
Hepatitis C virus (HCV), infecting 170 million people worldwide, is a major public health problem. In developing countries, unsafe injections and blood transfusions are thought to be the major routes of transmission. However, our previous work in a population from Egypt, endemic for HCV, revealed highly significant familial correlations, strongly suggesting the existence of both familial transmission of the virus...
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