Article
Fusion-induced malignancy? A preliminary study. (a challenge to today's common wisdom).
Neoplasma - 1 Jan 1992
Munzarová M, Lauerová L, Kovarík J, Rejthar A, Brezina V, Kellnerová R, Kovarík A
Abstract excerpt
Five fusions between mouse embryonic cells and syngeneic adult peritoneal macrophages were performed. The resulting hybrids as well as both parental cells (6 cultures of embryonal cells and 6 cultures of adult macrophages) were grown in vitro under the same culture conditions. All populations of explanted macrophages died during the second month in primary culture and five populations of cultured embryonic cells...
Topics
- 3T3 Cells
- Animals
- Cell Division
- Cell Fusion
- Cell Survival
- Cell Transformation, Neoplastic
- Cells, Cultured
- Chromosomes
- Embryo, Mammalian
- Hybrid Cells
- Macrophages