Article
The vascular endothelial growth factor (VEGF) +405G>C 5'-untranslated region polymorphism and increased risk of endometriosis in South Indian women: a case control study.
Human reproduction (Oxford, England) - 1 Jul 2005
Bhanoori Manjula, Arvind Babu K, Pavankumar Reddy N G, Lakshmi Rao K, Zondervan Krina, Deenadayal Mamata, Kennedy Stephen, Shivaji S
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor (VEGF), a major mediator of angiogenesis and vascular permeability, is known to play a key role in the pathophysiology of endometriosis. METHODS AND RESULTS: The single nucleotide polymorphisms, -460C>T and +405G>C, in the 5'-untranslated region of the VEGF gene were tested for association in a case-control study of 215 affected women and 210 women with no evidence...
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