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Article

Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy.

American journal of respiratory and critical care medicine - 1 Nov 2004

Poon Audrey H, Laprise Catherine, Lemire Mathieu, Montpetit Alexandre, Sinnett Donna, Schurr Erwin, Hudson Thomas J

Abstract excerpt

Genome scans for asthma have identified suggestive or significant linkages on 17 different chromosomes, including chromosome 12, region q13-23, housing the vitamin D receptor (VDR) gene. Through interaction with VDR, 1,25-dihydroxyvitamin D3 mediates numerous biological activities, such as regulation of helper T-cell development and subsequent cytokine secretion profiles. Variants of the VDR have been found to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15282199
DOI: 10.1164/rccm.200403-412OC

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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