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Article

A susceptibility gene for premature ovarian failure (POF) maps to proximal Xq28.

European journal of human genetics : EJHG - 1 Oct 2004

Rossetti Francesca, Rizzolio Flavio, Pramparo Tiziano, Sala Cinzia, Bione Silvia, Bernardi Franca, Goegan Mara, Zuffardi Orsetta, Toniolo Daniela

Abstract excerpt

Terminal deletions of the long arm of the human X chromosome have been described in women with premature ovarian failure (POF). We report here the molecular characterization of an inherited deletion in two affected women and in their mother. The two daughters presented secondary amenorrhea at 17 or 22 years respectively, while the mother was fertile. She had four children, but she eventually had premature...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15280899
DOI: 10.1038/sj.ejhg.5201186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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