Article
The yeast Apq12 protein affects nucleocytoplasmic mRNA transport.
RNA (New York, N.Y.) - 1 Sept 2004
Baker Kristian E, Coller Jeff, Parker Roy
Abstract excerpt
An important step in mRNA biogenesis is the export of mRNA from the nucleus to the cytoplasm. In this work, we provide evidence that the previously uncharacterized gene APQ12 functions in nucleocytoplasmic mRNA transport in Saccharomyces cerevisiae. First, apq12delta strains manifest 3' hyperadenylated mRNA similar to other previously characterized RNA export mutants. Second, bulk poly(A)+ RNA is retained in the...
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