Article
Genetic susceptibility of mice to Candida albicans vaginitis correlates with host estrogen sensitivity.
Infection and immunity - 1 Aug 2004
Clemons Karl V, Spearow Jimmy L, Parmar Rachana, Espiritu Marife, Stevens David A
Abstract excerpt
We compared susceptibility to Candida vaginitis in derived murine substrains differing in sensitivity to estrogen (CD-1 and CD10, resistant; CD3 and C57BL/6 responsive), and in F1 crosses. The order of decreasing resistance was CD-1 > or = CD10 > or = CD10 x CD3F1 > CD10 x B6F1 > CD3 > C57BL/6 and correlated with estrogen responsiveness in endocrine disruptor assays. Resistance to Candida vaginitis appears...
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