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Article

Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis.

Infection and immunity - 1 Jul 2004

Hurd Elizabeth A, Domino Steven E

Abstract excerpt

Fut2-LacZ-null mice, which are a model of the human ABO and Lewis nonsecretor group, display increased susceptibility to experimental yeast vaginitis, indicating a role for alpha(1,2)fucosylated cervical glycans in mucosal defense. However, the lack of significant effect of competitive inhibition...

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Identifiers

PMID: 15213174
DOI: 10.1128/IAI.72.7.4279-4281.2004
PMCID: PMC427463

Genes

ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15213174-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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