Article
Immunostimulatory CpG Oligodeoxynucleotide Confers Protection in a Murine Model of Infection withBurkholderia pseudomallei
22 Jul 2004
Abstract excerpt
Although CpG oligodeoxynucleotides (CpG ODNs) are known to enhance resistance against infection in a number of animal models, little is known about the CpG-induced protection against acute fatal sepsis such as that associated with the highly virulent bacterium Burkholderia pseudomallei. We previously demonstrated in an in vitro study that immunostimulatory CpG ODN 1826 enhances phagocytosis of B. pseudomallei and...
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