Article
Molecular mechanisms of cholesteryl ester transfer protein deficiency in Japanese.
Journal of atherosclerosis and thrombosis - 1 Jan 2004
Nagano Makoto, Yamashita Shizuya, Hirano Ken-Ichi, Takano Mayumi, Maruyama Takao, Ishihara Mitsuaki, Sagehashi Yukiko, Kujiraoka Takeshi, Tanaka Kazuya, Hattori Hiroaki, Sakai Naohiko, Nakajima Norimichi, Egashira Tohru, Matsuzawa Yuji
Abstract excerpt
Plasma cholesteryl ester transfer protein (CETP) facilitates the transfer of cholesteryl ester (CE) from high density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins. Since CETP regulates the plasma levels of HDL cholesterol and the size of HDL particles, CETP is considered to be a key protein in reverse cholesterol transport (RCT), a protective system against atherosclerosis. The importance of...
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