Article
Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels.
The Journal of clinical investigation - 15 Jun 1996
Zhong S, Sharp D S, Grove J S, Bruce C, Yano K, Curb J D, Tall A R
Abstract excerpt
Plasma high density lipoprotein (HDL) levels are strongly genetically determined and show a general inverse relationship with coronary heart disease (CHD). The cholesteryl ester transfer protein (CETP) mediates the transfer of cholesteryl esters from HDL to other lipoproteins and is a key partici...
Topics
- Aged
- Asian
- Carrier Proteins
- Cholesterol Ester Transfer Proteins
- Cholesterol Esters
- Cholesterol, HDL
- Coronary Disease
- Glycoproteins
- Humans
- Japan
- Male
- Mutation