Article
Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol.
The Journal of clinical investigation - 1 Nov 1994
Inazu A, Jiang X C, Haraki T, Yagi K, Kamon N, Koizumi J, Mabuchi H, Takeda R, Takata K, Moriyama Y
Abstract excerpt
Genetic determinants of HDL cholesterol (HDL-C) levels in the general population are poorly understood. We previously described plasma cholesteryl ester transfer protein (CETP) deficiency due to an intron 14 G(+1)-to-A mutation(Int14 A) in several families with very high HDL-C levels in Japan. Su...
Topics
- Adult
- Aged
- Alleles
- Amino Acid Sequence
- Base Sequence
- Carrier Proteins
- Cholesterol Ester Transfer Proteins
- Cholesterol, HDL
- Glycoproteins
- Humans
- Male