Article
[Case-only study on the relationship between genetic polymorphisms in toxicant metabolizing enzymes and risk of occupational chronic benzene poisoning].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Jun 2004
Zhang Zhong-bin, Wan Jun-xiang, Xia Zhao-lin
Abstract excerpt
OBJECTIVE: To explore the effects of interaction between environmental exposure factors and genetic polymorphism in toxicant metabolizing enzymes on risk of occupational chronic benzene poisoning. METHODS: One hundred and fifty-two cases of chronic benzene poisoning were analyzed for the risk by case-only study. RESULTS: The frequency of non-null GSTT1 gene in benzene poisoning workers with moderate benzene...
Topics
- Adult
- Benzene
- Cytochrome P-450 CYP2E1
- Female
- Genetic Predisposition to Disease
- Genotype
- Glutathione Transferase
- Humans
- Male
- Middle Aged
- NAD(P)H Dehydrogenase (Quinone)
- Occupational Diseases
- Polymerase Chain Reaction