Article
Aggregation of mycobacteria caused by disruption of fibronectin-attachment protein-encoding gene.
FEMS microbiology letters - 15 Jul 2004
Miyamoto Yuji, Mukai Tetsu, Takeshita Fumihiko, Nakata Noboru, Maeda Yumi, Kai Masanori, Makino Masahiko
Abstract excerpt
The fibronectin-attachment protein (FAP) is conserved among several species of mycobacteria. Although this protein is associated with attachment and internalization of bacteria to host cells via fibronectin, the physiological role of the protein still remains unclear. To investigate this point, we generated FAP gene disruptant in Mycobacterium smegmatis. The gene disruption, verified by Southern blot and PCR...
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