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Article

Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis.

Arthritis and rheumatism - 1 Jul 2004

Newton Julia L, Harney Sinéad M J, Timms Andrew E, Sims Anne-Marie, Rockett Kirk, Darke Chris, Wordsworth B Paul, Kwiatkowski Dominic, Brown Matthew A

Abstract excerpt

OBJECTIVE: We have previously identified a single-nucleotide polymorphism (SNP) haplotype involving the lymphotoxin alpha (LTA) and tumor necrosis factor (TNF) loci (termed haplotype LTA-TNF2) on chromosome 6 that shows differential association with rheumatoid arthritis (RA) on HLA-DRB1*0404 and *0401 haplotypes, suggesting the presence of additional non-HLA-DRB1 RA susceptibility genes on these haplotypes. To...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15248209
DOI: 10.1002/art.20358

Genes

LTA
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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