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Article

Werner syndrome protein 1367 variants and disposition towards coronary artery disease in Caucasian patients.

Mechanisms of ageing and development - 1 Jul 2004

Bohr Vilhelm A, Metter E Jeffery, Harrigan Jeanine A, von Kobbe Cayetano, Liu Ji Lan, Gray Matthew D, Majumdar Alokes, Wilson David M, Seidman Michael M

Abstract excerpt

The leading causes of death for individuals with Werner syndrome (WS) are myocardial infarction (MI) and stroke. The WS gene encodes a nuclear protein with both helicase and exonuclease activities. While individuals with WS have mutations that result in truncated, inactive proteins, several seque...

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Identifiers

PMID: 15246744
DOI: 10.1016/j.mad.2004.05.001

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15246744-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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