Article
Molecular basis of predisposition to develop type 1 diabetes mellitus in North Indians.
Tissue antigens - 1 Aug 2004
Rani R, Sood A, Goswami R
Abstract excerpt
Type 1 diabetes (T1D) mellitus is a multifactorial autoimmune disease where more than 90% of insulin-producing pancreatic beta cells are destroyed before the clinical manifestations, warranting a need to identify the children predisposed to get the disease. Of the 20 genomic intervals implicated for the risk to develop T1D, the major histocompatibility complex (MHC) region on chromosome 6p21.31 (IDDM1) has been...
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