Article
Development and clinical evaluation of a highly sensitive DNA microarray for detection and genotyping of human papillomaviruses.
Journal of clinical microbiology - 1 Jul 2004
Oh Tae Jeong, Kim Chang Jin, Woo Suk Kyung, Kim Tae Seung, Jeong Dong Jun, Kim Myung Soon, Lee Sunwoo, Cho Hyun Sill, An Sungwhan
Abstract excerpt
Human papillomavirus (HPV) has been found in cervical cancer, tonsillar cancer, and certain types of head and neck cancers. We report on a DNA microarray-based method for the simultaneous detection and typing of HPVs. The genotype spectrum discriminated by this HPV DNA microarray includes 15 high-risk HPV genotypes and 12 low-risk HPV genotypes. The HPV DNA microarray showed high degrees of specificity and...
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