Article
Detection of human papillomavirus genotypes with liquid bead microarray in cervical lesions of northern Chinese patients.
Cancer genetics and cytogenetics - 1 Apr 2008
Li Ying, Wang Yipeng, Jia Chanwei, Ma Yanmin, Lan Yonglian, Wang Shuyu
Abstract excerpt
Human papillomavirus (HPV) is the main cause of cervical cancer. Blending multiplex polymerase chain reaction (PCR) amplification and multiplex hybridization to liquid bead microarray (LBMA), we detected and identified 25 common HPV genotypes using type-specific primers for HPV E6 and E7 genes in cervical lesions of northern Chinese patients. Of the 511 cervical samples, 349 (68.3%) were found to be HPV positive...
Topics
- Adult
- Aged
- Alphapapillomavirus
- China
- DNA, Viral
- Female
- Genotype
- Human papillomavirus 6
- Humans
- Middle Aged
- Polymerase Chain Reaction